Is rituximab “The Wonder Drug” for antineutrophil cytoplasmic antibodies-associated vasculitis?
نویسندگان
چکیده
منابع مشابه
Pulmonary Fibrosis in Antineutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis
Pulmonary fibrosis (PF) is an uncommon manifestation observed in patients with antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV), particularly microscopic polyangiitis (MPA). While patients with PF associated with AAV seem to e Brun, MD, Philip D, avid Saadoun, MD, PhD patients with PF associated with AAV, fulfilling the American College of Rheumatology criteria and/or Ch...
متن کاملRefractory disease in antineutrophil cytoplasmic antibodies associated vasculitis.
PURPOSE OF REVIEW Induction treatment of antineutrophil cytoplasmic antibodies (ANCA) associated vasculitis (AAV) is not always successful and nonresponding patients are considered refractory. RECENT FINDINGS Refractory disease should be subdefined to the treatment that was received. Cyclophosphamide refractory AAV occurs in up to 5% of patients. Many more patients develop contraindications t...
متن کاملTreatment of antineutrophil cytoplasmic antibody-associated vasculitis.
PURPOSE OF REVIEW The primary idiopathic small-vessel vasculitis syndromes include granulomatosis with polyangiitis, Churg-Strauss syndrome, and microscopic polyangiitis. These disorders are commonly referred to as antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides and prominently affect the pulmonary vasculature. Although significant progress has been made in the management of ...
متن کاملSpotlight on rituximab in the treatment of antineutrophil cytoplasmic antibody-associated vasculitis: current perspectives
A 54-year-old patient presented to his general practitioner because of strong muscle pain in both thighs. Inflammatory parameters (CRP 16.3 mg/dL) and white blood cells (15 g/L) were elevated. The patient reported a weight loss of 10 kg in 4 weeks. There was no fever or any other specific symptoms. Urine dipstick examination and computed tomography of the chest were unremarkable. Because of inc...
متن کاملPredictive value of antineutrophil cytoplasmic antibodies in small-vessel vasculitis.
OBJECTIVE . The predictive value of antineutrophil cytoplasmic antibodies (ANCA) as markers of clinical activity of small vessel vasculitis is controversial. We reviewed the outcome of patients with ANCA-associated vasculitis from a single center and evaluated the predictive value of ANCA as markers of relapse. METHODS The medical history of all consecutive patients with ANCA-associated vascu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian Journal of Rheumatology
سال: 2019
ISSN: 0973-3698
DOI: 10.4103/0973-3698.254190